New antimicrobial agent broadens preservation possibilities in cosmetic formulations

Preservatives are frequently associated with contact allergy in cosmetic products or drugs. Quaternium-15 and formaldehyde are among the top ten allergens - based on prevalence rate and clinical significance - listed in 2013 by the North American Contact Dermatitis Group (NACDG). In addition to those, four other preservatives - diazolidinyl urea (DIAZ), parabens, imidazolidinyl urea, methylchloroisothiazolinone (CMIT)/ methylisothiazolinone (MIT) - are among the top 20 allergens also listed by NACDG, which results in restrictions imposed by global regulatory agencies. Indeed, consumer exposure to a list of preservative substances that is increasingly shorter can result in a higher incidence of primary sensitization, as the same preservative is used in a wide range of cosmetic products concomitantly.

This creates a paradox for formulators, as it is increasingly difficult to reduce allergic reactions and contact dermatitis in the medium and long-term based on a little-diversified palette of preservatives.

There are few safe alternatives that can meet the needs of these professionals. Recent developments include sugar, fatty acid and amino acid-derived ingredients, with excellent biological compatibility, also contributing to a good sensorial experience and stability of cosmetic formulations, functioning as emollients, humectants, solubilizers and coemulsifiers.

Hebeatol^®​CG​ is a new functional ingredient acting as a broad-spectrum antimicrobial agent, providing formulators with greater chances of diversification in terms of product preservation. With a great synergetic combination of xylitol esters and caprylyl glycol, Hebeatol^®​CG​ is compatible with several cosmetic formulations which are great for micellar waters, wet wipes and eyelash mascaras.

Developed by Chemyunion, Hebeatol^®​CG​ complements the Hebeatol^®​​ range, composed by Hebeatol^®​Plus, Hebeatol^®​BA, and Hebeatol^®​PS VG versions. Benefits: Uses 100% biodegradable molecules obtained from renewable sources; Repairs skin barrier, reducing transepidermal water loss by 21%; Synergetic and unique combination between a new safe, effective, green molecule and a well-known preservative, approved in several countries for cosmetic use; Formulations for skin care and hair care.

Benefits:

• Uses 100% biodegradable molecules obtained from renewable sources;
• Repairs skin barrier, reducing transepidermal water loss by 21%;
• Synergetic and unique combination between a new safe, effective, green molecule and a well-known preservative, approved in several countries for cosmetic use;
• Formulations for skin care and hair care.